HOME > Publications

Main Publication List
  1. Ando H, Hirose M, Kurosawa G, Impey S, Mikoshiba K. Time-lapse imaging of microRNA activity reveals the kinetics of microRNA activation in single living cells. Sci Rep. 7(1): 12642. (2017)
  2. Tanaka M, Wang X, Mikoshiba K, Hirase H, Shinohara Y. Rearing-environment-dependent hippocampal local field potential differences in wildtype and inositol trisphosphate receptor type 2 knockout mice. J Physiol. 595(20):6557-6568. (2017)
  3. Sugawara T, Hisatsune C, Miyamoto H, Ogawa N, Mikoshiba K. Regulation of spinogenesis in mature Purkinje cells via mGluR/PKC -mediated phosphorylation of CaMKIIβ. Proc Natl Acad Sci U S A. 114(26): E5256-E5265. (2017)
  4. Hamada K, Miyatake H, Terauchi A, Mikoshiba K. IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography. Proc Natl Acad Sci U S A. 114(18): 4661-4666. (2017)
  5. Kabayama H, Tokushige N, Takeuchi M, Kabayama M, Fukuda M, Mikoshiba K. Parkin promotes proteasomal degradation of synaptotagmin IV by accelerating polyubiquitination. Mol Cell Neurosci. 80:89-99. (2017)
  6. Sherwood MW, Arizono M, Hisatsune C, Bannai H, Ebisui E, Sherwood JL, Panatier A, Oliet SH, Mikoshiba K. Astrocytic IP3 Rs: Contribution to Ca2+ signalling and hippocampal LTP. Glia 65(3): 502-513. (2017)
  7. Bonneau B, Ando H, Kawaai K, Hirose M, Takahashi-Iwanaga H, Mikoshiba K. IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact. Elife 19896. (2016)
  8. Yamada Y.†‡, Matsumoto Y., Okahara N, and * Mikoshiba K.‡ †Co-first author, Co-corresponding author Chronic multiscale imaging of neuronal activity in the awake common marmoset Scientific Reports 6:35722. (2016)
  9. Miyamoto A, Sugiura K, * Mikoshiba K. * Development of a convenient and supersensitive high-throughput screening system for genetically encoded fluorescent probes of small molecules using a confocal microscope. Cell Calcium S0143-4160(16)30113-0. (2016)
  10. Monai H, Ohkura M, Tanaka M, Oe Y, Konno A, Hirai H, Mikoshiba K, Itohara S, Nakai J, Iwai Y, Hirase H. Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain. Nature Communications  (2016) doi: 10.1038/ncomms11100.
  11. Kim SK, Hayashi H, Ishikawa T, Shibata K, Shigetomi E, Shinozaki Y, Inada H, Roh SE, Kim SJ, Lee G, Bae H, Moorhouse AJ, Mikoshiba K, Fukazawa Y, Koizumi S, Nabekura J. Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain.  J Clinical Investigation 126(5): 1983-97 (2016)
  12. Bannai H, Niwa F, Sherwood M.W, Shrivastava A.N, Arizono M, Miyamoto A, Sugiura K, Lévi S,TrillerA, Mikoshiba K. Bidirectional control of synaptic GABAAR clustering by glutamate and calcium. Cell Reports  13:1-3 (2015)
  13. Tsuboi D, Kuroda K, Tanaka M, Namba T, Iizuka Y, Taya S, Shinoda T, Hikita T, Muraoka S, Iizuka M, Nimura A, Mizoguchi A, Shiina N, Sokabe M, Okano H, Mikoshiba K, Kaibuchi K.Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity. Nature Neurosci. 18(5): 698-707. (2015)
  14. Kawaai K, Mizutani A, Shoji H, Ogawa N, Ebisui E, Kuroda Y, Wakana S, Miyakawa T, Hisatsune C, Mikoshiba K.RBIT regulates CaMKIIα activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation. Proc Natl Acad Sci U S A. 112(17):5515-20. (2015)
  15. Hisatsune C, Ebisui E, Usui M, Ogawa N, Suzuki A, Mataga N, Takahashi-Iwanaga H, Mikoshiba K.ERp44 Exerts Redox-Dependent Control of Blood Pressure at the ER. Molecular Cell 1015-27. (2015)
  16. Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K. IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis. J Clinical Investigation 125(8):3269-79. (2015)
  17. Hashimoto M, Nara T, Hirawake H, Morales J, Enomoto M, Mikoshiba K. Antisense Oligonucleotides Targeting Parasite Inositol 1,4,5-Trisphosphate Receptor Inhibits Mammalian Host Cell Invasion by Trypanosoma cruzi. Scientific Reports 4: 4231 (2014)
  18. Hamada K, Terauchi A, Nakamura K, Higo T, Nukina N, Matsumoto N, Hisatsune C, Nakamura T, Mikoshiba K. Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptors. Proc Natl Acad Sci U S A. 111(38):E3966-75. (2014).
  19. Klar J, Hisatsune C, Baig SM, Tariq M, Johansson AC, Rasool M, Malik NA, Ameur A, Sugiura K, Feuk L, Mikoshiba K, Dahl N. Abolished InsP3R2 function inhibits sweat secretion in both humans and mice.J Clinical Investigation 124(11): 4773-80. (2014)
  20. Hashimoto M, Enomoto M, Morales J, Kurebayashi N, Sakurai T, Hashimoto T, Nara T, Mikoshiba K. Inositol 1,4,5-Trisphosphate receptor regulates replication, differentiation, infectivity, and virulence of the parasitic protist Trypanosoma cruzi. Molecular Microbiololgy 87(6): 1133-50 (2013)
  21. Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S. Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice. Gastroenterology 145(1): 232-241 (2013)
  22. Sugawara T, Hisatsune C, Le TD, Hashikawa T, Hirono M, Hattori M, Nagao S, Mikoshiba K. Type 1 inositol trisphosphate receptor regulates cerebellar circuits by maintaining the spine morphology of Purkinje cells in adult mice. J Neuroscience 33(30): 12186-96 (2013)
  23. Arizono M, Bannai H, Nakamura K, Niwa F, Enomoto M, Matsu-Ura T, Miyamoto A, Sherwood MW, Nakamura T, Mikoshiba K. Receptor-selective diffusion barrier enhances sensitivity of astrocytic processes to metabotropic glutamate receptor stimulation. Science Signaling 5(218): ra27. (2012a)
  24. Hamada K, Mikoshiba K. Revisiting channel allostery: a coherent mechanism in IP3 and ryanodine receptors. Science Signaling 5(225): pe24. (2012b)
  25. Kuroda Y, Hisatsune C, Mizutani A, Ogawa N, Matsuo K, Mikoshiba K. Cot Kinase Promotes Ca2+ Oscillation/Calcineurin-independent Osteoclastogenesis by Stabilizing NFATc1 Protein. Molecular and Cellular Biology 32(14): 2954-63. (2012)
  26. Mikoshiba K. The Discovery and structural investigation of the IP3 receptor and the associated IRBIT protein. Adv Exp Med Biol. Vol 740: Springer; 2012: 281-304.
  27. Nakamura H, Bannai H, Inoue T, Michikawa T, Sano M, Mikoshiba K. Cooperative and stochastic calcium releases from multiple calcium puff sites generate calcium microdomains in intact HeLa cells.J.Biol.Chem. 287(29):24563-72. (2012)
  28. Niwa F, Bannai H, Arizono M, Fukatsu K, Triller A, Mikoshiba K. Gephyrin-Independent GABA(A)R Mobility and Clustering during Plasticity. PLoS One 7(4): e36148. (2012)
  29. Sato-Miyaoka M, Hisatsune C, Ebisui E, Ogawa N, Takahashi-Iwanaga H, Mikoshiba K. Regulation of hair shedding by the type 3 IP3 receptor. J. Invest Dermatol. 132(9):2137-47. (2012)
  30. Yamashita N, Ohshima T, Nakamura F, Kolattukudy P, Honnorat J, Mikoshiba K, Goshima Y. Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization. J. Neuroscience 32(4):1360-5. (2012)
  31. Yamazaki Y, Fujii S, Aihara T, Mikoshiba K. Activation of inositol 1, 4, 5-trisphosphate receptors during preconditioning low-frequency stimulation leads to reversal of long-term potentiation in hippocampal CA1 neurons. Neuroscience 207:1-11. (2012)
  32. Gerasimenko JV, Lur G, Ferdek P, Sherwood MW, Ebisui E, Tepikin AV, Mikoshiba K, Petersen OH, Gerasimenko OV. Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors. Proc Natl Acad Sci U S A. 108(14): 5873-8. (2011a)
  33. Goto J, Mikoshiba K. Inositol 1,4,5-trisphosphate receptor-mediated calcium release in purkinje cells: from molecular mechanism to behavior. Cerebellum 10(4): 820-33. (2011)
  34. Kabayama H, Takeuchi M, Taniguchi M, Tokushige N, Kozaki S, Mizutani A, Nakamura T, Mikoshiba K. Syntaxin 1B suppresses macropinocytosis and semaphorin 3A-induced growth cone collapse. J. Neuroscience 31(20): 7357-64. (2011a)
  35. Lur G, Sherwood MW, Ebisui E, Haynes LP, Feske S, Sutton R, Burgoyne R, Mikoshiba K, Petersen OH, Tepikin AV. InsP3 receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences. Biochemical J. 436(2): 231-9. (2011)
  36. Maul-Pavicic A, Chiang SC, Rensing-Ehl A, Jessen B, Fauriat C, Wood SM, Sjoqvist S, Hufnagel M, Schulze I, Bass T, Schamel WW, Fuchs S, Pircher H, McCarl CA, Mikoshiba K, Schwarz K, Feske S, Bryceson YT, Ehl S. ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis. Proc Natl Acad Sci U S A. 108(8): 3324-9. (2011b)
  37. Nakamura TY, Jeromin A, Mikoshiba K, Wakabayashi S. Neuronal calcium sensor-1 promotes immature heart function and hypertrophy by enhancing Ca2+ signals. Circulation Research 109(5): 512-23. (2011)
  38. Nakazawa M, Uchida K, Aramaki M, Kodo K, Yamagishi C, Takahashi T, Mikoshiba K, Yamagishi H. Inositol 1,4,5-trisphosphate receptors are essential for the development of the second heart field. J Mol Cell Cardiol. 51(1): 58-66. (2011)
  39. Sasakawa N, Ohara-Imaizumi M, Fukuda M, Mikoshiba K, Kumakura K. Dissociation of inositol polyphosphates from the C2B domain of synaptotagmin facilitates spontaneous release of catecholamines in adrenal chromaffin cells. A suggestive evidence of a fusion clamp by synaptotagmin. Neuropharmacology 60(7-8): 1364-70. (2011)
  40. Satoh K, Matsu-Ura T, Enomoto M, Nakamura H, Michikawa T, Mikoshiba K. Highly cooperative dependence of sarco/endoplasmic reticulum calcium ATPase (SERCA) 2a pump activity on cytosolic calcium in living cells. J Biological Chemistry 286(23): 20591-9. (2011)
  41. Shinohara T, Michikawa T, Enomoto M, Goto JI, Iwai M, Matsu-Ura T, Yamazaki H, Miyamoto A, Suzuki A, Mikoshiba K., Mechanistic basis of bell-shaped dependence of inositol 1,4,5-trisphosphate receptor gating on cytosolic calcium. Proc Natl Acad Sci U S A. 108(37) :15486-91(2011)
  42. Yang D, Li Q, So I, Huang CL, Ando H, Mizutani A, Seki G, Mikoshiba K, Thomas PJ, Muallem S. IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway. J. Clin Invest. 121(3): 956-65. (2011)
  43. Horikawa K, Yamada Y, Kobayashi K, Hashimoto M, Matsu-ura T, Miyawaki A, Michikawa T, Mikoshiba K, Nagai T Spontaneous network activitiy visualized by ultra-sensitive Ca2+ indicators, yellow cameleon-Nano. Nature Methods 7(9):729-32. (2010)
  44. Higo T, Hamada K, Nakamura T, Hattori M, Mikoshiba K, Mechanism of ER stress-induced brain damage by IP3 receptor. Neuron 68(5):865-78. (2010)
  45. Uchida K, Aramaki M, Nakazawa M, Yamagishi C, Makino S, Fukuda K, Nakamura T, Takahashi T,Mikoshiba K, Yamagishi H. Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis. PLoS One 5(9) e12500 (2010)
  46. Nakayama H, Bodi I, Maillet M, Desantiago J, Domeier TL, Mikoshiba K, Lorenz JN, Blatter LA, Bers DM, Molkentin JD. The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. Circulation Research 107(5):659-66. (2010)
  47. Suzuki M, Van Paesschen W, Stalmans I, Horita S, Yamada H, Bergmans BA, Legius E, Riant F, De Jonghe P, Li Y, Sekine T, Igarashi T, Fujimoto I, Mikoshiba K, Shimadzu M, Shiohara M, Braverman N, Al-Gazali L, Fujita T, Seki G. Defective membrane expression of the Na+-HCO3- cotransporter NBCe1 is associated with familial migraine. Proc Natl Acad Sci USA. 107(36):15963-8. (2010)
  48. Bannai H, Levi S, Schweizer C, Inoue T, Launey T, Racine V, Sibarita JB, Mikoshiba K, Triller A. Activity-dependent tuning of inhibitory neurotransmission based on GABAAR diffusion dynamics. Neuron 62(5): 670-82. (2009)
  49. Yang D, Shcheynikov N, Zeng W, Ohana E, So I, Ando H, Mizutani A, Mikoshiba K. Muallem S. IRBIT coordinates epithelial fluid and HCO3-secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct. J. Clin Invest. 119(1): 193-202 (2009)
  50. Akiyama H, Matsu-ura T, Mikoshiba K, and Kamiguchi H., Control of neuronal growth cone navigation by asymmetric inositol 1,4,5-trisphosphate signals. Science Signaling 2(79): ra34. (2009)
  51. Higazi DR, Fearnley CJ, Drawnel FM, Talasila A, Corps EM, Ritter O, McDonald F, Mikoshiba K, Bootman MD, Roderick HL Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes. Molecular Cell 33(4): 472-82 (2009)
  52. Gerasimenko JV, Lur G, Sherwood MW, Ebisui E, Tepikin AV, Mikoshiba K, Gerasimenko OV, Petersen OH. Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors. Proc. Natl. Acad. Sci. USA 106(26): 10758-63. (2009)
  53. Kuroda Y., Hisatsune C., Nakamura T., Matsuo K., Mikoshiba K.: Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis Proc. Natl. Acad. Sci. USA 105(25): 8643-48 (2008)
  54. Mizutani A., Kuroda Y., Futatsugi A., Furuichi T. and Mikoshiba K.: Phosphorylation of Homer3 by Calcium/Calmodulin-Dependent Kinase II Regulates a Coupling State of Its Target Molecules in Purkinje Cells. J. Neurosci. 28(20): 5369-5382 (2008)
  55. Ohshima, T., Hirosawa, M., Tabata, H., Mutoh, T., Adachi, T., Suzuki, H., Saruta, K., Iwasato, T., Itohara, S., Hashimoto, M., Nakajima, K., Ogawa, M., Kulkaruni, A.B., Mikoshiba K. Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development 134(12): 2273-2282 (2007)
  56. Shirakabe K, Priori G, Yamada H, Ando H, Horita S, Fujita T, Fujimoto I, Mizutani A, Seki G, Mikoshiba K IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1). Proc Natl Acad Sci U S A 103(25): 9542-9547 (2006)
  57. Ando, H., Mizutani, A., Kiefer, H., Tsuzurugi, D., Michikawa, T., Mikoshiba K. IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on IP3 receptor in a phosphorylation-dependent manner. Molecular Cell 22: 795-806 (2006)
  58. Higo, T., Hattori, M., Nakamura, T., Natsume, T., Michikawa, T., Mikoshiba K. Subtype-specific and ER-lumenal-environment-dependent Regulation of Inositol 1,4,5-Trisphosphate Receptor Type 1 by ERp44. Cell 120: 85-98 (2005)
  59. Bosanac, I., Yamazaki, H., Matsu-ura, T., Michikawa, T., Mikoshiba K., Ikura, M. Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. Molecular Cell 17: 193-203 (2005)
  60. Futatsugi, A., Nakamura, T., Yamada, M. K., Ebisui, E., Nakamura, K., Uchida, K., Kitaguchi, T., Takahashi-Iwanaga, H., Noda, T., Aruga, J. & Mikoshiba K.: IP3 Receptor Types 2 and 3 mediate exocrine secretion underlying energy metabolism Science 309:2232-2234 (2005)
  61. Fan-Yan Wei, Nagashima, K., Oshima, T., Saheki, Y., Matsushita, M., Yamada, Y., Mikoshiba K., Seino, Y., Tomozawa, K. Cdk5-dependent regulation of glucose-stimulates insulin secretion. Nature Medicine 11: 1104-1108 (2005)
  62. Sato, C., Hamada, K., Ogura, T., Miyazawa, A., Iwasaki, K., Hiroaki, Y., Tani, K., Terauchi, A., Fujiyoshi, Y. & Mikoshiba, K.: Inositol 1, 4, 5-trisphosphate Receptor contains Multiple cavities and L-shaped Ligand-binding domains. J. Mol. Biol. 336:155-164 (2004)
  63. Hashimoto, M. & Mikoshiba K.: Neuronal birthdate-specific gene transfer with adenoviral vectors. J. Neurosci. 24 (1):286-296 (2004)
  64. Bannai, H., Inoue, T., Nakamura, T., Hattori, M., Mikoshiba, K., : Kinesin dependent, rapid , bidirectional transport of ER sub-compartment in dendrites of neurous. J. Cell Sci. 117:163-175 (2004)
  65. Hamada, K., Terauchi, A. & Mikoshiba, K.: Three-dimensional rearrangements within inositol 1,4,5-trisphosphate receptor by calcium. J. Biol. Chem. 278 (52) 52881-52889 (2003)
  66. Hashimoto, M. & Mikoshiba K.: Mediolateral compartment of the cerebellum is determined on the “Birth Date” of Purkinje cells. J. Neurosci. 23 (36) 11342-11351 (2003)
  67. Herrera, E., Brown, L., Aruga, J., Rachel, R.A., Dolen, G., Mikoshiba K., Brown,X., Mason, C.A. Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell 114 545-557 (2003)
  68. Nagai, T., Ibata, K., Park, ES., Kubota, M., Mikoshiba K., Miyawaki, A. A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nature Biotechnol. 20: 87-90 (2002)
  69. Saneyoshi, T., Kume, S., Amasaki, Y., Mikoshiba K. The Wnt/Calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos. Nature 417: 295-299 (2002)
    Bosanac, I., Alattia, J. R., Mal, T. K., Chan, J., Talarico, S., Tong, F. K., Tong, K. I., Yoshikawa, F.,
  70. Furuichi, T., Iwai, M., Michikawa, T., Mikoshiba K., Ikura, M. Structure of the IP3 receptor binding core in complex with IP3. Nature 420: 696-700 (2002)
  71. Fukami K, Nakao K, Inoue T, Kataoka Y, Kurokawa M, Fissore RA, Nakamura K, Katsuki M, Mikoshiba K, Yoshida N, Takenawa T Requirement of phospholipase Cdelta4 for the zona pellucida-induced acrosome reaction. Science 292: 920-923 (2001)
  72. Fujii, S., Matsumoto, M., Igarashi, K., Kato, H. & Mikoshiba, K.: Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors. Learning & Memory 7: 312-320 (2000)
  73. Ma, H.T., Patterson, R.L., van Rossum, D.B., Birnbaumer, L., Mikoshiba K., Gill, D.L. Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels. Science 287: 1647-51 (2000)
  74. Nishiyama M, Hong K, Mikoshiba K, Poo MM, Kato K Calcium stores regulate the polarity and input specificity of synaptic modification. Nature 408(6812): 584-588 (2000)
  75. Yoshikawa, F., Iwasaki, H., Michikawa, T., Furuichi, T. & Mikoshiba, K.: Trypsinized cerebellar inositol 1,4,5-trisphosphate receptor. Structural and functional coupling of cleaved ligand binding and channel domains. J.Biol.Chem. 274 316-327 (1999)
  76. Futatsugi, A., Kato, K., Ogura, H., Li, S-T., Nagata, E., Kuwajima, G., Tanaka, T., Itohara, S., Mikoshiba K. Facilitation of NMDA receptor-independent LTP and spatial learning in mutant mice lacking Ryanodine receptor type 3. Neuron 24: 701-713 (1999)
  77. Michikawa, T., Hirota, J., Kawano, S., Hiraoka, M., Yamada, M., Furuichi, T., Mikoshiba K.: Calmodulin mediates calcium-dependent inactivation of the cerebellar type 1 inositol1,4,5-trisphosphate receptor. Neuron 23 799-808 (1999)
  78. Inoue, T., Kato, K., Kohda, K. & Mikoshiba, K.: Type 1 inositol 1,4,5-trisphosphate receptor is required for induuction of long-term depression in cerebellar Purkinje neurons. J.Neurosci. 18 5366-73 (1998)
  79. Takei, K., Shin, R.-M., Inoue, T., Kato, K., Mikoshiba K. Regulation of nerve growth mediated byinositol 1,4,5-trisphosphate receptor in growth cones. Science 282: 1705-708 (1998)
  80. Zhao, H., Ivic, L., Otaki, J.M., Hashimoto, M., Mikoshiba K., Firestein, S. Functional expression of a mammalian odorant receptor. Science 279: 237-242 (1998)
  81. Kume, S., Muto, A., Inoue, T., Suga, K., Okano, H., Mikoshiba K. Role of inositol 1,4,5-trisphosphate receptor in ventral signaling in Xenopus embryos. Science 278: 1940-43 (1997)
  82. Umemori, H., Inoue, T., Kume, S., Sekiyama, N., Nagao, M., Itoh, H., Nakanishi, S., Mikoshiba K., Yamamoto, T. Activation of the G protein Gq/11 through tyrosine phosphorylation of the a subunit. Science 276: 1878-82 (1997)
  83. Sheldon, M., Rice, S.D., D’ Arcangelo, G., Yoneshima, H., Nakajima, K., Mikoshiba K., Howell, W.B., Cooper, A,J., Goldowitz, D., Curran, T. Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice. Nature 389 730-733 (1997)
  84. Del Rio, J.A., Heimrich, B., Borrell, V., Forster, E., Drakew, A., Alcantara, S., Nakajima, K., Miyata, T., Ogawa, M., Mikoshiba K., Derer, P., Frotscher, M., Soriano, E.: A role for Cajal-Retzius cells and reelin in the development of hippocampal connections. Nature 385: 70-74 (1997)
  85. Matsumoto, M., Nakagawa, T., Inoue, T., Nagata, E., Tanaka, K., Takano, H., Minowa, O., Kuno, J., Sakakibara, S., Yamada, M., Yoneshima, H., Miyawaki, A., Fukuuchi, Y., Furuichi, T., Okano, H.,
  86. Mikoshiba K., Noda, T. Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature 379: 168-171 (1996)
  87. Muto, A., Kume, S., Inoue, T., Okano, H., Mikoshiba K.: Calcium waves along the cleavage furrows in cleavage-stage xenopus Embryos and its inhibition by heparin. J. Cell Biol. 135 181-190 (1996)
  88. Ogawa, M., Miyata, T., Nakajima, K., Yagyu, K., Seike, M., Ikenaka, K., Yamamoto, H., Mikoshiba K.: The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron 14 899-912 (1995)
  89. Kagawa, T., Ikenaka, K., Inoue, Y., Kuriyama, S., Tsujii, T., Nakao, J., Nakajima, K., Aruga, J., Okano, H., Mikoshiba K.: Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene. Neuron 13 427-442 (1994)
  90. Fujita, Y., Mynlieff, M., Dirksen, R.T, Kim, M.S., Niidome, T., Nakai, J., Friedrich, T., Iwabe, N., Miyata, T., Furuichi, T., Furutama, D., Mikoshiba K., Mori, Y., Beam, K.G. Primary structure and functional expression of the w-conotoxin-sensitive N-type calcium channel from rabbit brain. Neuron 10: 585-598 (1993)
  91. Kume, S., Muto, A., Aruga, J., Nakagawa, T., Michikawa, T., Furuichi, T., Nakade, S., Okano, H., Mikoshiba K.: The Xenopus IP3 receptor: structure, functiion, and localization in oocytes and eggs Cell 73 555-570 (1993)
  92. Mikoshiba K. Inositol 1,4,5-trisphosphate receptor. Trends in Pharmacol. Sci. 14: 86-89 (1993)
    Miyazaki, S., Yuzaki, M., Nakada, K., Shirakawa, H., Nakanishi, S., Nakade, S., Mikoshiba K.: Block of Ca2+wave and Ca2+ oscillation by antibody to the inositol 1,4,5-trisphosphate receptor in fertilized hamster eggs. Science 257 251-255 (1992)
  93. Kuwajima, G., Futatsugi, A., Niinobe, M., Nakanishi, S., Mikoshiba K. Two types of ryanodine receptors in mouse brain: Skeletal muscle type exclusively in Purkinje cells and cardiac muscle type in various neurons. Neuron 9: 1133-42 (1992)
  94. Maeda, N., Kawasaki,T., Nakade, S., Yokota, N.,Taguchi,T., Kasai,M. & Mikoshiba, K.: Structural and functional characterization of inositol 1,4,5-trisphosphate receptor channel from mouse cerebellum. J. Biol. Chem. 266 1109-16 (1991)
  95. Mikoshiba K., Okano, H., Tamura, T., Ikenaka, K. Structure and function of myelin protein genes. Annual Rev. of Neurosci. 14: 201-217 (1991)
  96. Turnley, A.M., Morahan, G., Okano, H., Bernard, O., Mikoshiba K., Allison, J., Bartlett, P.F., Miller.,J.F.A.P. Dysmyelination in transgenic mice resulting from expression of class I histocompatibility molecules in oligodendrocytes. Nature 353: 566-69 (1991)
  97. Miyawaki, A., Furuichi, T., Maeda, N., Mikoshiba K.: Expressed cerebellar-type inositol 1,4,5-trisphosphate receptor, P400 has calcium release activity in a fibroblast L cell line. Neuron 5 11-18 (l990)
  98. Furuichi, T., Yoshikawa, S., Miyawaki, A., Wada, K., Maeda, N., Mikoshiba K.: Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400. Nature 342: 32-38 (1989)
  99. Mikoshiba K., Yokoyama, M., Inoue, Y., Takamatsu, K., Tsukada, Y., Nomura, T. Oligodendrocyte abnormalities in shiverer mouse mutant are determined in primary chimaeras. Nature 299: 357-359 (1982)
  100. Mikoshiba, K., Huchet, M. & Changeux, J.-P.: Biochemical and immunological studies on the P400 protein, a protein characteristic of the Purkinje cell from mouse and rat cerebellum. Developmental Neuroscience 2 254-275 (1979)
Last update: 11/17/2017